Total Cholesterol Formula:
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The Total Cholesterol formula calculates overall cholesterol levels from HDL, LDL, and triglyceride measurements. It provides a comprehensive assessment of cholesterol status in the body.
The calculator uses the Total Cholesterol formula:
Where:
Explanation: The formula combines direct measurements of HDL and LDL with an estimation of VLDL cholesterol derived from triglyceride levels (TG/5).
Details: Total cholesterol measurement is crucial for assessing cardiovascular risk, monitoring lipid-lowering therapy effectiveness, and guiding dietary and lifestyle interventions.
Tips: Enter HDL, LDL, and triglyceride values in mg/dL. All values must be valid (≥0). For accurate results, use fasting lipid panel measurements.
Q1: Why divide triglycerides by 5 in the formula?
A: This division estimates VLDL cholesterol, as VLDL typically carries about 20% of its mass as cholesterol (hence TG/5 approximates VLDL-C).
Q2: What are desirable total cholesterol levels?
A: Generally, <200 mg/dL is desirable, 200-239 mg/dL is borderline high, and ≥240 mg/dL is high risk.
Q3: When should cholesterol be measured?
A: Fasting samples (9-12 hours) are ideal for accurate triglyceride measurement, though non-fasting samples can be used for total cholesterol estimation.
Q4: Are there limitations to this calculation?
A: The formula becomes less accurate with very high triglyceride levels (>400 mg/dL) and in certain metabolic conditions.
Q5: How often should cholesterol be checked?
A: Adults should have cholesterol checked every 4-6 years, or more frequently if risk factors exist or treatment is ongoing.