1. What is the Cholesterol Calculation?

The cholesterol calculation estimates total cholesterol (TC) from HDL, LDL, and triglyceride values using the formula: TC = HDL + LDL + (TG / 2.2). This provides a comprehensive assessment of cholesterol levels in mmol/L format.

2. How Does the Calculator Work?

The calculator uses the cholesterol equation:

Where:

• \( TC \) — Total cholesterol (mmol/L)
• \( HDL \) — High-density lipoprotein (mmol/L)
• \( LDL \) — Low-density lipoprotein (mmol/L)
• \( TG \) — Triglycerides (mmol/L)

Explanation: The equation combines the three main cholesterol components to provide a complete picture of cholesterol status, with triglycerides converted to cholesterol equivalent units.

3. Importance of Cholesterol Calculation

Details: Accurate cholesterol assessment is crucial for evaluating cardiovascular risk, determining appropriate treatment strategies, and monitoring the effectiveness of cholesterol-lowering interventions.

4. Using the Calculator

Tips: Enter HDL, LDL, and triglyceride values in mmol/L. All values must be valid (≥0). The calculator will compute the total cholesterol value.

5. Frequently Asked Questions (FAQ)

Q1: Why divide triglycerides by 2.2?
A: This conversion factor accounts for the cholesterol content in very-low-density lipoproteins (VLDL), which carry most triglycerides in the blood.

Q2: What are optimal cholesterol levels?
A: Generally, TC < 5.2 mmol/L is desirable, 5.2-6.2 is borderline high, and >6.2 is high. However, individual targets may vary based on overall cardiovascular risk.

Q3: When should cholesterol be measured?
A: Fasting samples (9-12 hours) are ideal for accurate triglyceride measurement, though non-fasting samples can be used for TC, HDL, and LDL assessment.

Q4: Are there limitations to this calculation?
A: The formula assumes a constant relationship between triglycerides and VLDL cholesterol, which may vary in certain conditions like hypertriglyceridemia.

Q5: How often should cholesterol be checked?
A: Adults should have cholesterol checked every 4-6 years, or more frequently if risk factors are present or treatment is ongoing.