1. What is LDL-C Calculation?

The Friedewald formula estimates LDL cholesterol (LDL-C) from total cholesterol, HDL cholesterol, and triglyceride measurements. LDL-C >130 mg/dL is considered high and may indicate increased cardiovascular risk.

2. How Does the Calculator Work?

The calculator uses the Friedewald formula:

Where:

• \( TC \) — Total cholesterol (mg/dL)
• \( HDL \) — HDL cholesterol (mg/dL)
• \( TG \) — Triglycerides (mg/dL)

Interpretation: LDL-C >130 mg/dL is considered high and may warrant lifestyle changes or medical intervention.

3. Importance of LDL-C Calculation

Details: LDL cholesterol is a major risk factor for cardiovascular disease. Accurate estimation helps assess cardiovascular risk and guide treatment decisions.

4. Using the Calculator

Tips: Enter total cholesterol, HDL cholesterol, and triglyceride values in mg/dL. All values must be valid (>0). Note: This formula is less accurate when triglycerides >400 mg/dL.

5. Frequently Asked Questions (FAQ)

Q1: Why is LDL-C important?
A: LDL-C is often called "bad cholesterol" because high levels contribute to plaque buildup in arteries, increasing heart disease and stroke risk.

Q2: What are optimal LDL-C levels?
A: Generally, <100 mg/dL is optimal, 100-129 mg/dL is near optimal, 130-159 mg/dL is borderline high, 160-189 mg/dL is high, and ≥190 mg/dL is very high.

Q3: When should this formula not be used?
A: The Friedewald formula is less accurate when triglycerides >400 mg/dL, in non-fasting samples, or in certain conditions like type III hyperlipoproteinemia.

Q4: How can I lower my LDL-C?
A: Lifestyle changes include a heart-healthy diet, regular exercise, maintaining a healthy weight, and quitting smoking. Medications like statins may be prescribed when needed.

Q5: How often should cholesterol be checked?
A: Adults should have cholesterol checked every 4-6 years. Those with risk factors or existing heart conditions may need more frequent testing.